Calyculin A, protein phosphatase inhibitor from Abcam

Product Specs
ItemCalyculin A, protein phosphatase inhibitor
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab141784
Quantity10 UG, 50 UG
Purity0.99
Typeinhibitor

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Actomyosin Activity and Piezo1 Activity Synergistically Drive Urinary System Fibroblast ActivationAdvanced science (Weinheim, Baden-Wurttemberg, Germany)November 1, 2023Chen G, Gao X, Chen J, Peng L, Chen S, Tang C, Dai Y, Wei Q, Luo D.TAIJIA biotech, TJ8434), Yoda1 (0.1 µm, MedChemExpress, HY‐18723), Calyculin A (Calyc, 0.1 nm, Abcam, ab141784), (‐)‐Blebbistatin (20 µm, MERCK, B0560), and LY29004(0.1 nm, Abcam, ab120243). Polyethylene Glycol

(2) Switch of cell migration modes orchestrated by changes of three-dimensional lamellipodium structure and intracellular diffusionNat CommunAugust 24, 2023Chao Jiang, Hong-Yu Luo, Xinpeng Xu, Shuo-Xing Dou, Wei Li, Dongshi Guan, Fangfu Ye, Xiaosong Chen, Ming Guo, Peng-Ye Wang, et al.70-kD rhodamine B-dextran (D1841) were from Molecular Probes. Blebbistatin (ab120425) and Calyculin A (ab141784) were from Abcam. Latrunculin A and Jasplakinolide were from Sigma-Aldrich. Other chemicals were from

(3) Desmosome-anchored intermediate filaments facilitate tension-sensitive RhoA signaling for epithelial homeostasisbioRxivApril 1, 2023Bageshri Naimish Nanavati, Ivar Noordstra, Suzie Verma, Kinga Duszyc, Kathleen J. Green, Alpha S. Yapwas increased by treating 90–100% confluent Caco-2 cell monolayers with 100nM/mL calyculinA (Abcam #ab141784) for 10–15 min at 37°C. Induction of apoptosis a. Laser injury E-cad-GFP Caco2 cells were cultured

(4) Dynamic physiological α-synuclein S129 phosphorylation is driven by neuronal activityNPJ Parkinson's diseaseJanuary 16, 2023Ramalingam N, Jin SX, Moors TE, Fonseca-Ornelas L, Shimanaka K, Lei S, Cam HP, Watson AH, Brontesi L, Ding L, et al.bicuculline (Sigma #505875), tetrodotoxin (Cayman #14964), BI2536 (Selleckchem #S1109), Calyculin A (Abcam #ab141784), DL-AP5 (Tocris #0105), CNQX (Tocris #0190), FK506 (Tocris #3631), digitonin (Sigma #D141), nimodipine

(5) Viral Manipulation of a Mechanoresponsive Signaling Axis Disassembles Processing BodiesMolecular and Cellular BiologyOctober 26, 2021Elizabeth L. Castle, Carolyn-Ann Robinson, Pauline Douglas, Kristina D. Rinker, Jennifer A. Corcoran(B0560),10 μM,30 min Calyculin A,"Inhibition of MLC phosphatase, resulting in cell contraction",Abcam (ab141784),"2.5 nM, 5 nM",20 min Bafilomycin A1,"Inhibition of autophagosome-lysosome fusion, blocking final

(6) The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancerCellJune 10, 2021Vervoort SJ, Welsh SA, Devlin JR, Barbieri E, Knight DA, Offley S, Bjelosevic S, Costacurta M, Todorovski I, Kearney CJ, et al.(1,10-Phenanthroline-5,6-dione) was purchased from Sigma Aldrich (496383) and reconstituted in DMSO. Calyculin A (ab141784) and Okadaic Acid (ab120375) were purchased from Abcam and reconstituted in DMSO. Cytarabine was obtained

(7) Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanismsThe Biochemical journalFebruary 12, 2021Malik AU, Karapetsas A, Nirujogi RS, Mathea S, Chatterjee D, Pal P, Lis P, Taylor M, Purlyte E, Gourlay R, et al.purchased from Invitrogen (#A15202). GZD-824 was purchased from Cayman Chemical (#21508) and calyculin A (#ab141784) was purchased from Abcam, Inc. Phorbol 12-myristate 13-acetate (PMA) (#P8139), interleukin-1A (#I2778),

(8) Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleusNature communicationsMay 1, 2020Nastały P, Purushothaman D, Marchesi S, Poli A, Lendenmann T, Kidiyoor GR, Beznoussenko GV, Lavore S, Romano OM, Poulikakos D, et al.M1404): 1 μg/ml for 30 min., Blebbistatin (Merk, Cat. B0560): 25 μM for 15 min., Calyculin A (Abcam, Cat. ab141784): 50 nM for 15 min. Afterward, the cells were fixed with 4%PFA/PBS and immunofluorescence was performed. Statistics

(9) PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteinseLifeOctober 30, 2019Berndsen K, Lis P, Yeshaw WM, Wawro PS, Nirujogi RS, Wightman M, Macartney T, Dorward M, Knebel A, Tonelli F, et al.by Natalia Shpiro (University of Dundee) as described previously (Fell et al., 2015). Calyculin A (ab141784) and Okadaic Acid (ab120375) were purchased from Abcam. Microcystin-LR was obtained from Enzo Life Sciences

(10) Human cytomegalovirus phosphoproteins are hypophosphorylated and intrinsically disorderedJournal of General VirologyApril 1, 2017Franz J. J Rieder, Marie-Theres Kastner, Markus Hartl, Martin G Puchinger, Martina Schneider, Otto Majdic, William J. Britt, Kristina Djinović-Carugo, Christoph Steiningerwith different phosphatase inhibitors as indicated for the respective experiment (Calyculin A (CA) ab141784, Abcam, Cambridge, UK; Okadaic Acid (OKA), Calbiochem; Tacrolimus (FK506), Astellas Pharma, Munich,

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Calyculin A, protein phosphatase inhibitor from Abcam

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Calyculin A, protein phosphatase inhibitor from Abcam

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